Research & Development: Page 2
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New tau candidates, including an RNA therapy from Voyager, drive a multi-pronged Alzheimer’s approach
Voyager Therapeutics’ progress with drug candidates targeting tau marks a step in how the industry is walking multiple paths toward new therapeutic options.
By Michael Gibney • March 4, 2025 -
Teva targets schizophrenia to build on innovative medicines growth
The company is leaning on its subcutaneous technology to deliver long-acting options that could prevent patients from cycling through drugs.
By Meagan Parrish • Feb. 28, 2025 -
Explore the Trendline➔
Stock via Getty ImagesTrendlineClinical trial diversity
As pharma wises up to the fact that the current playbook for improving clinical trial diversity has yet to make a meaningful impact, the quest is on to refine that approach.
By PharmaVoice staff -
Q&A
AI deals are surging, and Recursion’s ongoing Exscientia merger points to a new world of integration
Recursion CFO Ben Taylor discusses the state of AI M&A and what companies should look for as the industry moves to new data technologies and systems.
By Michael Gibney • Feb. 27, 2025 -
Cancer vaccines have stumbled, but the approach is gaining new steam
The number of candidates in development has nearly doubled over the past 15 years.
By Kelly Bilodeau • Feb. 26, 2025 -
Its CEO died. The company scrapped a promising program. Now, for their 2nd act.
Terns Pharmaceuticals sees blockbuster promise for two potential best-in-class molecules in obesity and oncology.
By Alexandra Pecci • Feb. 25, 2025 -
Incentivizing rare disease R&D is getting tougher, but revamped policies could turn the tide
Orphan drug development has long been incentivized by government policy. But as the financial math shifts, so do the risks of bringing rare disease drugs to market.
By Michael Gibney • Feb. 25, 2025 -
Q&A
Merck, Lilly launch manufacturing R&D consortium to help ‘bolster’ U.S. production
The Young Institute Pharmaceutical Manufacturing Consortium will research and develop new production technologies.
By Alexandra Pecci • Feb. 19, 2025 -
Biotech Spotlight
CRISPR’s cardio catch-all drives a biotech’s broad potential
Scribe Therapeutics hopes to prevent cardiometabolic diseases by targeting underlying causes with CRISPR technology.
By Kelly Bilodeau • Feb. 18, 2025 -
In the crowded cardio space, it’s David vs. Goliath for small biotechs
What will it take for a clinical-stage biotech to break into the cardio space? One CEO thinks he has the answer.
By Alexandra Pecci • Feb. 11, 2025 -
Are orexins the next golden child of neuroscience?
An emerging class of orexin-based drugs are on the cusp of disrupting care for sleep disorders — and potentially much more.
By Meagan Parrish • Feb. 10, 2025 -
Q&A // Biotech Spotlight
Beyond GLP-1s? This biotech is exploring longer-term metabolic treatments
Fractyl Health is entering pivotal studies for a procedure that aims to be an ‘off ramp’ to GLP-1s and exploring how a one-time, ‘smart GLP-1’ gene therapy can Treat type 2 diabetes.
By Amy Baxter • Feb. 10, 2025 -
As financial headwinds pick up, pharmas are aiming to squeeze more ROI from their R&D
With assets under a knife and pipelines under a microscope, R&D programs are being overhauled to be more efficient and cost effective.
By Alexandra Pecci • Feb. 5, 2025 -
What should pharma make of the FDA going dark on DEI?
After a series of potent executive orders last week, the FDA removed draft guidance on diversity in clinical trials.
By Meagan Parrish • Feb. 4, 2025 -
Drugmakers prep for bird flu outbreak, despite continued low risk
While the virus hasn’t made a sustained leap into humans, vaccines and treatments are coming through the pipes if it does.
By Kelly Bilodeau • Feb. 3, 2025 -
Deep Dive
A new, non-opioid pain drug is here. Getting it to patients could be agony.
After decades of research, Vertex Pharmaceuticals now has an approved pain medication. Can one of the world’s most powerful biotechs contend with a healthcare system that’s long favored opioids?
By Jacob Bell • Feb. 3, 2025 -
Year in Preview
Pharma’s forecast for 2025: Sowing seeds of a rebound
Despite regulatory uncertainty, pharma is bouncing back from a market slump and is being fueled by innovation.
By Meagan Parrish • Jan. 31, 2025 -
Is federal funding frozen? Has it already thawed? Flip-flop leaves biopharma on edge
NIH grants that help fund drug development were caught in the mix of confusing executive orders this week.
By Amy Baxter • Jan. 31, 2025 -
A long-awaited alternative to opioids is on the FDA doorstep. Can Vertex seal the deal?
Vertex Pharmaceuticals’ non-opioid pain medication is up for FDA approval this week. Other drugmakers have found safer alternatives to expand the pain management landscape.
By Amy Baxter • Updated Feb. 4, 2025 -
Natural killer cells, a rising alternative to CAR-T cell therapy
These innate immune cells may provide a safer, lower-cost option in cancer and autoimmune diseases.
By Kelly Bilodeau • Jan. 27, 2025 -
Gene therapies have been uneven for DMD — but these companies hope to turn the tide
Despite mixed results using gene therapies to treat Duchenne muscular dystrophy, drug developers are pushing ahead with the belief the answer could come down to delivery.
By Meagan Parrish • Jan. 24, 2025 -
J&J is all in on tau-targeted Alzheimer’s candidates. Will the approach lead to more effective treatments?
Anti-tau candidates haven’t crossed the regulatory threshold like their anti-amyloid counterparts, but J&J’s clinical efforts could lead in the right direction.
By Michael Gibney • Jan. 23, 2025 -
After an obesity stumble, BioAge reconnects with its longevity pipeline
The company is kicking off the year with a new Novartis partnership and renewed focus on metabolic aging targets.
By Alexandra Pecci • Jan. 22, 2025 -
Innovate or perish: Industry’s evolution leaves little room for me-too approaches
Novel drug approvals have set the stage for more breakthroughs in pharma.
By Amy Baxter • Updated Jan. 22, 2025 -
Deep Dive
‘The bar has risen’: China’s biotech gains push US companies to adapt
Pharma dealmaking for drugs invented in China is putting pressure on U.S. biotechs to compete harder.
By Ben Fidler • Jan. 17, 2025 -
Musk’s rare disease torpedo, hospitals’ pharma fix and other policies leaders are tracking
There’s more to pharma's regulatory story in 2025 than just the IRA.
By Meagan Parrish • Jan. 17, 2025